| 12:00 |
Registration |
| 13:00-14:00 |
Lunch |
| 14:00 |
Welcome |
| 14:00-15:00 |
Opening Lecture Harald Stenmark (Oslo, Norway) Phosphoinositide and Rab dependent membrane contact sites and their role in endosome motility and neurite outgrowth |
| 15:00-17:15 |
SESSION 1 - Intracellular Transport and Communication in the Regulation of Cell Signaling Chairs: Simona Polo & Emilio Hirsh Emiliana Tognon (Milan) Increased V-ATPase expression to support Notch signaling during stem cells establishment in Drosophila Caterina Lucano (Milan) A novel role of the endocytic adaptor proteins Eps15 and Eps15L1 in the regulation of Notch signaling Filippo Acconcia (Rome) Clathrin heavy chain-based pathway is involved in the regulation of 17β-estradiol-induced cell proliferation Alexia Conte (Milan) Defining the interplay between EGFR endocytosis and signaling through predictive modeling and wet-lab experiments Michol Savio (Milan) Identifying DUBs in the EGFR pathway Eelco van Anken (Milan) Acute and chronic stress signaling from the endoplasmic reticulum Sowmya Lakshminarayanan (Padua) Genome wide screen to identify ER-mitochondria tether proteins using FRET biosensors Riccardo Filadi (Padua) Presenilin-2 is a master regulator of endoplasmic reticulum-mitochondria tethering Gaia Gherardi (Padua) The role of the Mitochondrial Calcium Uniporter in the control of skeletal muscle mass |
| 17:15-17:45 |
Coffee break |
| 17:45-19:15 |
Poster Session |
| 19:15-19:45 |
Election of next vice-chair |
| 20:00 |
Dinner |
| 8:30-9:30 |
Opening Lecture Nuno Raimundo (Goettingen, Germany) Mitochondrial signaling - the energy factory takes control of the boardroom |
| 9:30-10:30 |
SESSION 2 - Mitochondrial Signaling and Calcium Homeostasis Chairs: Rosario Rizzuto & Eelco Van Anken Maria Patron (Padua) MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effect on MCU activity Renata Tisi (Milan) Characterization of ER-involving hypotonic shock-induced calcium release in the budding yeast Lena Pernas (Padua) Toxoplasma effector MAF1 mediates recruitment of host mitochondria and impacts the host response Tatiana Varanita (Padua) The multifunctional mitochondrial inner membrane protein Optic Atrophy 1 controls cellular damage in vivo |
| 10:30-11:00 |
Coffee break |
| 11:00-12:30 |
SESSION 3 - Cell Signaling in Cancer and Disease Chairs: Paola De Filippi & Letizia Lanzetti Miriam Martini (Turin) Loss of PI3K-C2A promotes tumorigenesis and aneuploidy in breast cancer Chiara Malinverno (Milan) RAB5A in the control of mammary epithelial morphogenesis and motility Silvia Grasso (Turin) p140Cap limits ERBB2 breast cancer progression by regulating apical basal cell polarity Chiara Recchi (London, United Kingdom) The Tumor Suppressor OPCML regulates EMT and cell motility in ovarian cancer through its interaction with Receptor Tyrosine Kinases Roberto Coppo (Turin) ESDN/DCBLD2/CLCP1 coordiantes melanoma progression Valentina Masola (Padua) Heparanase is a player in the renal fibrosis by regulating TGF-β expression and activity |
| 12:30 |
Closing Remarks |
| 13:00-14:00 |
Lunch |

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11/05/2014

3 March 2014
to
15 April 2014
New deadline
10 March 2014
to
16 April 2014
Sara Sigismund, Milan
Rosario Rizzuto, Padua